Health

Could Insulin Pills Prevent Diabetes? Big Study Seeks Answer

Published

10 years ago

July 3, 2015

This photo taken Wednesday, May 13, 2015, shows insulin pills taken by Hayden Murphy, 13, who is participating in a study in Plainfield, Ill. to try to prevent or at least delay Type 1 diabetes. (AP Photo/Nam Y. Huh)

LINDSEY TANNER, AP Medical Writer

CHICAGO (AP) — For nearly a century, insulin has been a life-saving diabetes treatment. Now scientists are testing a tantalizing question: What if pills containing the same medicine patients inject every day could also prevent the disease?

Thirteen-year-old Hayden Murphy of Plainfield, Illinois, is helping researchers determine if the strategy works for Type 1 diabetes, the kind that is usually diagnosed in childhood. If it does, he might be able to avoid the lifetime burdens facing his 5-year-old brother, Weston. They includes countless finger pricks and blood sugar checks, and avoiding playing too hard or eating too little, which both can cause dangerous blood sugar fluctuations.

Hayden Murphy is among more than 400 children and adults participating in U.S. government-funded international research investigating whether experimental insulin capsules can prevent or at least delay Type 1 diabetes. Hospitals in the United States and eight other countries are involved and recruitment is ongoing. To enroll, participants must first get bad news: results of a blood test showing their chances for developing the disease are high.

“When I got the news, I was devastated,” Hayden said. He knows it means his life could change in an instant.

“He has the daily reminders. He sees what his brother goes through,” said the boys’ mom, Myra Murphy.

So now Hayden Murphy swallows a small white capsule daily and has his blood checked periodically for signs of diabetes.

“I hope it doesn’t come to me, and I really didn’t want it to come to him,” Hayden said.

A small, preliminary study by different researchers, published recently in the Journal of the American Medical Association, suggests the approach might work. Children who took insulin pills showed immune system changes that the researchers said might help prevent diabetes. The study was too small and didn’t last long enough to know for sure.

The ongoing larger study is more rigorous, randomly assigning participants to get experimental insulin capsules or dummy pills, and should provide a clearer answer.

“Does it prevent indefinitely? Does it slow it down, does it delay diabetes? That also would be a pretty big win,” said Dr. Louis Philipson, a University of Chicago diabetes specialist involved in the study.

About 1.25 million Americans have Type 1 diabetes. Type 2 disease is more common, affecting nearly 30 million nationwide and most of the more than 300 million worldwide with diabetes. Besides short-term complications from poorly controlled blood sugar, both types raise long-term risks for damage to the kidneys, heart and eyes.

Both types are increasing and for Type 2, experts think that’s because of rising obesity and inactivity. But the upward trend in Type 1 diabetes, increasing worldwide by at least 3 percent each year, is more perplexing.

“We know so very little about the exact mechanisms that cause Type 1 diabetes,” which complicates efforts to prevent it, said Dr. Desmond Schatz, the study’s chair and medical director of the University of Florida Diabetes Center.

“For the most part, it’s really shooting an arrow into a field and hoping one of the arrows hits a target,” Schatz said.

In Type 1 diabetes, the pancreas stops making insulin, a blood sugar-regulating hormone that helps the body convert sugar in food into energy. Treatment is lifetime replacement insulin, usually via injections or a small pump. In Type 2, the body can’t make proper use of insulin. It can sometimes be treated with a healthy diet and exercise.

Genes are thought to increase risks for Type 1 diabetes. Viruses and other infections are among factors suggested as possible triggers the disease, which causes the body’s immune system to attack insulin-producing cells.

Dr. Wendy Brickman, a diabetes specialist at Chicago’s Lurie Children’s Hospital who’s involved in the study, explained that researchers think taking insulin by mouth so that it’s digested like food might somehow trick the faulty immune system into not attacking insulin-making cells.

Insulin pills also are being studied as a diabetes treatment, but the challenge has been finding a way to get the drug to reach the bloodstream without being degraded as it is digested.

A branch of the National Institutes of Health is funding the prevention research, including two other studies: one involves infusions of the drug Orencia, approved for rheumatoid arthritis, another autoimmune disease; the other involves infusions of an experimental drug called teplizumab.

If prevention pills work, they’d likely be less expensive than having a lifetime of diabetes, said Lisa Spain, an institute scientist and program director. Results from the insulin pill prevention study are expected in 2017, she said, adding that it’s too soon to predict an outcome.

Hayden Murphy and his family are cautiously optimistic; after three years in the study, he’s shown no signs of diabetes. Still, his mom says she worries every time he seems thirstier than usual — among symptoms her youngest boy had before his diagnosis three years ago.

There’s a middle son, too — 9-year-old Daxton, who faces an increased diabetes risk because his little brother has it.

“It definitely is a life-changing diagnosis,” Myra Murphy said.

___

Study information: http://tinyurl.com/nfv3ql7

American Diabetes Association: http://www.diabetes.org

___

AP Medical Writer Lindsey Tanner can be reached at http://www.twitter.com/LindseyTanner

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Essay: Intentional Self Care and Community Connections Can Improve Our Wellbeing

At the deepest and also most expansive level of reality, we are all part of the same being, our bodies made from the minerals of the earth, our spirits infused by the spiritual breath that animates the universe. Willingness to move more deeply into fear and pain is the first step toward moving into a larger consciousness. Willingness to move beyond the delusion of our separateness can show us new ways of working and living together.

Published

1 month ago

October 27, 2025

Oakland Post

Lorraine Bonner is a retired physician. She is also a sculptor who works in clay, exploring issues of trust, trustworthiness and exploitation, as well as visions of a better world.

By Dr. Lorraine Bonner, Special to California Black Media Partners

I went to a medical school that was steeped in the principles of classical Western medicine. However, I also learned mindfulness meditation during that time, which opened me to the multifaceted relationship between illnesses and the interconnecting environmental, mental and emotional realities that can impact an individual’s health.

Therefore, when I began to practice medicine, I also pursued training in hypnosis, relaxation techniques, meditation, and guided imagery, to bring a mind-body focus to my work in medical care and prevention.

The people I saw in my practice had a mix of problems, including high blood pressure, diabetes, and a variety of pain issues. I taught almost everyone relaxation breathing and made some general relaxation tapes. To anyone willing, I offered guided imagery.

“My work embraced an approach to wellness I call “Liberatory Health” — one that not only addresses the treatment and management of disease symptoms but also seeks to dismantle the conditions that make people sick in the first place.”

From my perspective, illness is only the outermost manifestation of our efforts to cope, often fueled by addictions such as sugar, tobacco, or alcohol, shackled by an individualistic cult belief that we have only ourselves to blame for our suffering.

To put these ideas into practical form, I would quote the immortal Mr. Rogers: “Find the helpers.” There are already people in every community working for liberation. Some of them are running for office, others are giving food to those who need it. Some are volunteering in schools, libraries or hospitals. Some are studying liberation movements, or are working in urban or community gardens, or learning to practice restorative and transformative justice, or creating liberation art, music, dance, theater or writing. Some are mentoring high schoolers or apprenticing young people in a trade. There are many places where compassionate humans are finding other humans and working together for a better world.

A more compassionate world is possible, one in which we will all enjoy better health. Creating it will make us healthier, too.

In community, we are strong. Recognizing denial and overcoming the fragmenting effects of spiritual disorder offer us a path to liberation and true health.

Good health and well-being are the collective rights of all people!

About the Author

Dr. Lorraine Bonner is a retired physician. She is also a sculptor who works in clay, exploring issues of trust, trustworthiness and exploitation, as well as visions of a better world.

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Prescribing Prevention: Doctors Turn to Lifestyle, Herbs and Veggies to Protect Against Chronic Illness in Black Californians

Published

1 month ago

October 27, 2025

Oakland Post

Dr. Bill Releford owns Bloom Ranch in Acton, a 250-acre farm in Acton. Releford, a podiatrist based in Los Angeles started the 250-acre Bloom Ranch — he largest Black-owned ranch in Los Angeles County — in 2023. The ranch provides access to nutritional fruits and vegetables, a part of Releford’s strategy for focusing on wellness and preventive care.

By Charlene Muhammad, California Black Media

Leibo Glover received his diabetes diagnosis at the same time he found out he needed a below-the-knee amputation.

“Minor,” thought the 63-year-old.

Glover had been self-medicating a toe injury before seeing the doctor.

But while driving from South Los Angeles to Miami on a family trip, an infection set in.

“I had it but didn’t know,” said Glover. “I was just going to come back to California, but they told me if I had left, I would have come home as a corpse,” Glover told California Black Media (CBM).

A majority of the nearly 3.5 million Californians diagnosed with diabetes have preventable Type 2 diabetes, according to researchers at the UCLA Center for Health Policy Research.

In 2023, diabetes was diagnosed in 1 in 6 adults with the lowest incomes (16.7% at 0–99% of the federal poverty line), compared to 1 in 11 adults with the highest incomes (8.9% at 300% or more of the federal poverty line). Age is a factor, too: more than 1 in 5 older adults age 65 and over (22.3%) had diabetes, about twice the rate of adults age 18–64 (8.6%).

Another study by Health Economics and Evaluation Research (HEER) mapped patients with diabetes in California who had amputations. Researchers found that patients living in low-income ZIP codes were far more likely to have had lower-limb amputations than those in higher-income ZIP codes, essentially identifying amputation “hot spots.”

At the time of Glover’s 2018 diagnosis, he was experiencing housing instability and going through financial hardships. Now, he has more stable housing and he has improved his health through lifestyle changes like eating healthier and getting more sleep.

“If the equipment is right, I can stand on my leg for hours. I can actually run, jump, dance and all of that,” said Glover, who got his diabetes under control, in part, by avoiding carbohydrates and sugars.

As chronic illnesses continue to disproportionately impact Black Californians — often leading to preventable amputations and premature deaths — a growing number of doctors and advocates are expanding their care from just treatment to including prevention. From promoting diet and lifestyle changes to cultivating community farms focused on prevention and wellness like Dr. Bill Releford’s Bloom Ranch in Acton.

Releford, a podiatrist based in Los Angeles started the 250-acre Bloom Ranch in 2023 as part of his strategy for preventive care.

“This is my assignment,” said Releford.

“Bloom Ranch has been a perfect backdrop for me to be creative and to find avant-garde ways to make fresh fruits and vegetables more accessible to food deserts in Los Angeles County,” he stated.

California produces nearly half of the nation’s fruits and vegetables, yet more than 1 in 5 Californians — about 8.8 million people — currently struggle with food insecurity, according to the California Association of Food Banks.

“Studies have shown that 75% of amputations are preventable. And African Americans have the highest amputation rate in the nation,” Releford said.

As such, Releford continued, the mortality rate associated with high-level amputation is 50%, which means “if we had 10 people that all had high level amputations, five of those would be deceased in three years.”

Monday, June 28, 2025. Leibo Glover at his home in Los Angeles, California. The security professional’s leg was amputated below the knee.

Releford’s ranch is the largest Black-owned farm in L.A. County. He plans to partner with UCLA and the Charles R. Drew University of Medicine and Science to develop prescriptive vegetable boxes.

“Certain vegetables and herbs can lower blood pressure naturally, like beets, turnips, dill, basil, garlic and others,” said Releford.

“Hopefully, this will inspire other farmers to take this model and replicate it across other urban areas,” Releford added.

“A lot of studies have shown that gardening has so many health benefits – being in the sun, Vitamin D,” said Releford. “The dirt has a lot of microbes that are good for your immune system. Studies have shown that people who work in the dirt have strong immune systems.”

Gardening can potentially decrease the risk of dementia, enhance cognition, reduce stress, and boost immunity, indicates research by Genoa Barrow of the University of Southern California Center for Health Journalism as part of the 2024 Ethnic Media Collaborative, Healing California.

During a recent picturesque day at Bloom Ranch, families, school children, farmers and members of The Ultimate Book Club 1998, founded by Alina Anderson, sampled and purchased fresh produce while taking photographs.

“This is huge. “All of us have families that could use this information,” said Anderson.

Doctors like Releford, who are committed to tackling the most chronic diseases impacting all their patients utilize peer-to-peer support programs with self-management training led by individuals living with chronic conditions to provide role models and support for patients, according to a recent study by the California Health Care Foundation.

“The unifying feature of these programs is that they seek to build on the strengths, knowledge, and experience that peers can offer,” the report states.

Liz Helms, CEO of the California Chronic Care Coalition, addressed state-backed prevention policy and initiatives.

“It’s in horrible shape. It needs to get so much better, especially in underserved areas, where the Black population has a whole set of different needs,” she said.

Helms, who started advocacy after being denied access to care in the early 1990s, applauded new developments in telehealth. The opportunity to choose between visiting a doctor’s office or placing a phone call makes a difference, especially if there are transportation or distance issues, or if one is too sick, she said.

Fear is one thing people, especially in the Black community, must overcome, emphasized Helms.

“I had to get over my fear of going to the doctor, of not speaking up,” continued Helms, urging patients to “understand the baseline” of their health.

“Don’t let anyone stigmatize you or tell you that you’re not good enough to get care or look down on you. Everyone has a right to good, quality, affordable, timely health care,” said Helms.

To engage Bloom Ranch for preventive care focused on wellbeing and healthy living, call (323) 388-4828 or sign up at Bloomranchofacton.com

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A West Coast CDC? California Partners With Oregon, Washington and Hawaii to Form Regional Health Alliance

“President Trump’s mass firing of CDC doctors and scientists — and his blatant politicization of the agency — is a direct assault on the health and safety of the American people. California, Oregon, and Washington will not allow the people of our states to be put at risk,” said Governors Gavin Newsom, Tina Kotek, and Bob Ferguson in a joint statement.

Published

3 months ago

September 14, 2025

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By Bo Tefu, California Black Media

California, Oregon, and Washington have launched the West Coast Health Alliance, a regional initiative to provide unified, science-based guidance on immunizations and other public health policies. The alliance was created in response to federal actions that have undermined the independence of the Centers for Disease Control (CDC) and raised concerns about the politicization of science.

The alliance aims to ensure residents receive credible, evidence-based recommendations, free from political interference.

State health leaders emphasized the importance of transparency and evidence-based communication.

California Department of Public Health Director Erica Pan said, “The dismantling of public health and dismissal of experienced and respected health leaders and advisors, along with the lack of using science, data, and evidence to improve our nation’s health are placing lives at risk.”

Oregon Health Authority Director Sejal Hathi backed the coalition saying, “Our communities deserve clear and transparent communication about vaccines — communication grounded in science, not ideology.” Washington State Secretary of Health Dennis Worsham noted, “Public health at its core is about prevention — preventing illness, preventing the spread of disease, and preventing early, avoidable deaths.”

Hawaii has joined the alliance, expanding the partnership to four states. “Hawaii is proud to stand with our West Coast partners to ensure public health decisions are grounded in science, not politics,” said Gov. Josh Green.

The alliance states will coordinate health guidelines using trusted national medical organizations, aligning immunization recommendations and public health strategies while respecting tribal sovereignty. Shared principles to strengthen public confidence in vaccines and other health measures will be finalized in the coming weeks.