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UCSF Researchers Probe Link Between Bacteria and Asthma
By Jeffrey Norris, UC News
Infants exposed to a diverse range of bacterial species in house dust during the first year of life appear to be bless likely to develop asthma in early childhood, according to a new study published online on June 6, 2014, in the Journal of Allergy and Clinical Immunology.
Children who were neither allergic nor prone to wheezing as three-year-olds were the most likely to have been exposed to high levels of bacteria, and paradoxically, to high levels of common allergens.
In fact, some of the protective bacteria are abundant in cockroaches and mice, the source of these common allergens, according to UC San Francisco researcher Susan Lynch, PhD, a lead author for the multi-institutional study.
Lynch also found that exposure during the first year of life to household dust containing higher levels of two specific groups of bacteria that are abundant in the human gut – Bacteriodes and Firmicutes – was associated with less asthma risk in the analysis of data from 104 inner-city babies in four cities.
Lynch, an associate professor of medicine with the Division of Gastroenterology at UCSF, said there is no obvious mechanism explaining the association, but the evidence supports earlier research that strongly pointed to the influence of microbial species in shaping immune responses.
The new microbial research, led by Lynch and UCSF pulmonologist Homer Boushey, MD, a professor of medicine and an asthma expert at UCSF, as part of the larger Urban Environment and Childhood Asthma (URECA) study, led by James Gern, MD, a professor of pediatrics and medicine at the University of Wisconsin School of Medicine and Public Health in Madison. Researchers aim to discover reasons why asthma is more common and severe among children in poor inner cities.
“Early-life allergies and wheezing illnesses are the two main risk factors for childhood asthma,” Gern said.
To come up with their latest findings, the scientists compared exposure to allergens from cat, cockroach, dog, dust mite and mouse on one hand, and wheezing episodes as reported by parents and allergy as assessed by skin-prick tests on the other.
Through the first three years of life, cumulative exposure to allergy-provoking substances from cats, mice, cockroaches and dust mites – but not from dogs – was associated with more wheezing and allergic reaction in the new study. This was an expected result, based on earlier research.
But this association was reversed when the researchers analyzed exposures for just the first year of life, when greater exposure to certain allergens, those from cockroaches and mice, was associated with less risk of wheezing and allergy at three years.
These results indicate that immune responses might be shaped by exposures during the first year of life differently than they are by later exposures. “These findings suggest that concomitant exposure to high levels of certain allergens and bacteria in early life may be beneficial,” the researchers wrote in the journal paper.
If the study results are borne out in follow-up research in other populations, it might warrant testing of new strategies, Lynch said, including, “microbial supplementation to inoculate children in early life with appropriate microbes to help protect them against wheezing and allergy.”
Lynch’s own work and research by several others in the field has led her to become convinced that “the composition and function of the gut microbiome strongly influence immune reactions and present a novel avenue for development of therapeutics for both allergic asthma and a range of other diseases.”
According to Boushey, “Strict avoidance of allergens to lower asthma risk has been unsuccessful. Maybe permitting allergen exposures, with increased exposure to the sources of certain microbes, might be more successful in reducing asthma risk.”
Boushey noted that the research team’s new research associating increased bacterial diversity and abundance with lower risk appears to support the “hygiene hypothesis,” which suggests that the increase in the prevalence of allergies and asthma in modern, westernized countries might be an unintended consequence of children being exposed to fewer bacteria in cleaner indoor environments.
“If confirmed by other studies, these findings might even have us think of returning to the patterns of exposure of the 1940’s, when families were larger, food was less processed and sterilized, and children spent a lot of their time outdoors,” he said.
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Oakland Post: Week of June 18 – 24, 2025
The printed Weekly Edition of the Oakland Post: Week of June 18 – 24, 2025

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EXCLUSIVE OP-ED: President Joe Biden Commemorating Juneteenth
BLACKPRESSUSA NEWSWIRE — “I’ve always believed that we need to be honest about our history, especially in the face of ongoing efforts to erase it. Darkness can hide much, but it erases nothing. Only with truth can come healing, justice, and repair.”

By Joseph R. Biden, Jr.
46th President of the United States: 2021—2025
The people of Galveston, Texas, have been commemorating Juneteenth since the Civil War ended. Yesterday, in honor of the 160th anniversary, I went there to join them.
You can read about the events of Juneteenth, but there’s nothing quite like going to Galveston and seeing where it all happened.
After General Robert E. Lee surrendered at Appomattox Court House on April 9, 1865, Union troops marched across the South for two months, freeing enslaved people along the way. Their final stop was Galveston, an island off the Gulf coast of Texas. There, on June 19, 1865, Union troops went to Reedy Chapel, a church founded in 1848 by enslaved people, and posted a document titled simply “General Order #3.”
“The people of Texas are informed,” it said, “that, in accordance with a Proclamation from the Executive of the United States, all slaves are free.”
We can only imagine the joy that spread through Galveston – and across the state and nation – on that day and those that followed.
Yesterday, there was once again joy in Galveston, with a parade, picnic, and fireworks. There was also great solemnity, because Juneteenth is a sacred day – a day of weight and power.
The Book of Psalms tells us: “Weeping may endure for a night, but joy cometh in the morning.” Juneteenth marks both the long, hard night of slavery and subjugation, and the promise of that joyful morning to come.
As President, I had the great honor of signing the law declaring Juneteenth a federal holiday. It was our nation’s first new federal holiday since Martin Luther King, Jr. Day was created in 1983.
Our federal holidays say a lot about who we are as a nation. We have holidays celebrating our independence… the laborers who build this nation… the servicemembers who served and died in its defense.
And now, we also have a national holiday dedicated to the emancipation of enslaved Black Americans.
Signing that law was one of my proudest acts as President.
Yet for 156 years, Juneteenth was not written about in textbooks or taught in classrooms. Still today, there are those who say it does not deserve a holiday. They don’t want to remember the moral stain of slavery and the terrible harm it did to our country.
I’ve always believed that we need to be honest about our history, especially in the face of ongoing efforts to erase it. Darkness can hide much, but it erases nothing. Only with truth can come healing, justice, and repair.
I also believe that it’s not enough to commemorate the past. We must also embrace the obligation we have to the future. As Scripture says, “Faith without works is dead.” And right now, we Americans need to keep the faith and do the work.
In honor of Juneteenth, let’s help people register to vote.
For decades, we fought to expand voting rights in America. Now we’re living in an era when relentless obstacles are being thrown in the way of people trying to vote. We can’t let those tactics defeat us. In America, the power belongs with the people. And the way we show that power is by voting.
So let’s reach out to family, friends and neighbors – especially those who have never voted before. Remind them that with voting, anything is possible. And without it, nothing is possible.
Yesterday in Galveston, we gathered in Reedy Chapel to commemorate Juneteenth, just like people have done for 160 years and counting. We prayed, sang, and read General Order #3 again. The pews were full of families. How many people must have prayed for freedom inside those walls. How many must have sent fervent thanks to God when slavery finally ended.
I remembered the words of my late friend John Lewis. He said, “Freedom is not a state. It is an act.”
Juneteenth did not mark the end of America’s work to deliver on the promise of equality. It only marked the beginning. To honor the true meaning of Juneteenth, we must continue to work toward that promise. For our freedom. For our democracy. And for America itself.
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Cities Across the U.S. Shrink or Cancel Juneteenth Events as DEI Support Wanes
BLACKPRESSUSA NEWSWIRE — Across the country, Juneteenth celebrations are being scaled back or eliminated as public funding dries up and corporations withdraw sponsorship.

By Stacy M. Brown
Black Press USA Senior National Correspondent
Across the country, Juneteenth celebrations are being scaled back or eliminated as public funding dries up and corporations withdraw sponsorship. In many communities, the once-growing recognition of the holiday is facing sharp resistance tied to the unraveling of diversity, equity, and inclusion efforts.
In Denver, Colorado, the annual Juneteenth Music Festival, one of the largest in the nation—was cut from two days to one. Organizers said more than a dozen corporate sponsors walked away from commitments, leaving them with a financial gap that almost canceled the event. Norman Harris, the festival’s executive director, said several companies “pulled back their investments or let us know they couldn’t or wouldn’t be in a position to support this year.” Harris credited grassroots donors and small businesses for stepping in when larger backers stepped aside.
In Colorado Springs, the local celebration was relocated to the Citadel Mall parking lot after support from previous sponsors disappeared. Organizers noted that where there were once dozens of corporate partners, only five remained. The downsized event was pieced together with limited resources, but community leaders said they refused to let the holiday go unacknowledged.
Scottsdale, Arizona, canceled its Juneteenth observance after the city council voted to dissolve its diversity, equity, and inclusion office in February. Without the office in place, the city offered no support for planning or funding, leaving residents without an official celebration.
In San Diego, the Cooper Family Foundation lost a $25,000 grant from the National Endowment for the Arts that had been earmarked for Juneteenth programming. Organizers said the decision forced them to personally finance key elements of the event, including cultural exhibits, performances, and youth engagement activities.
Bend, Oregon, called off its Juneteenth event entirely. Organizers cited political tensions and safety concerns, saying they could not secure the partnerships needed to proceed. A public statement from the planning committee described the current climate as “increasingly volatile,” making it difficult to host a safe and inclusive event.
West Virginia, which has recognized Juneteenth as a paid state holiday since 2017, will not sponsor any official events this year. State leaders pointed to budget constraints and recent decisions to eliminate DEI programming across agencies as the reasons for stepping away from public observance.
Austin, Texas, has also reduced its Juneteenth programming. While the city has not canceled events outright, organizers said diminished city support and fewer private contributions forced them to focus only on core activities.
“Thankfully, there was a wide range of support that came when we made the announcement that the celebration is in jeopardy,” said Harris. “But it shows how fragile that support has become.”
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